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Percutaneous endoscopic procedure is a technique that can be used to treat patient that have gallstones, known as cholelithiasis, but cannot undergo surgery for gallbladder removal due to other medical issues. Often times these patients end up with a gallbladder drain, a cholecystostomy tube, that cannot be removed because of the risk of recurrent pain and symptoms.

Cryoablation uses extremely cold temperatures to kill cancer cells. Doctors started using it to treat small kidney cancer tumors as early as 1999, and the results have been extremely impressive.